Bio-safety cabinets are designed to provide personnel, environmental and product protection. Air flow is drawn around the operator into the front grille of the cabinet which provides personnel protection. Additionally, the downward laminar flow of HEPA-filtered air provides product protection by minimizing the chance of cross-contamination along the work surface of the cabinet. Because cabinet air passes through the exhaust HEPA filter, it is contaminant-free (environmental protection). All Class II cabinets are designed for work involving microorganisms assigned to bio safety levels 1, 2 and 3. Class II cabinets provide the microbe-free work environment necessary for cell culture propagation, and also may be used for the formulation of non-volatile antineoplastic or hemotherapeutic drugs. Bio safety cabinets are available in powder coated MS sheet and SS 304.

The downflow booth operates on a recirculatory airflow principle providing containment by air movement. A clean, constant, laminar downflow of Class 100 air is supplied in work area suppressing any dust clouds generated during open powder processing, removing and capturing airborne particles from the operator’s breathing zone. The Prefilters at the base of the rear wall, capture the airborne contaminants generated. Intake velocity at prefilters increases to ensure scavenging effect. A small percentage of air is discharged from the booth through the bleed exhaust HEPA filter to maintain the working space under negative pressure.